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B12 is water-soluble, so your body uses what it needs, stores a small amount in the liver, and passes most of the excess in urine

In the duodenum, vitamin B12 is freed from these binding proteins and transported throughout the body by intrinsic factor

E., Upadhyay, V., Turnbaugh, J

How it works KPV blocks the inflammation switch from reaching the cell nucleus, lowering production of inflammatory molecules (NF-B signaling)

By blocking NNMT, 5-Amino-1MQ prevents nicotinamide methylation, allowing NAD+ levels to rise and methyl groups to remain available for histone methylation and other epigenetic processes

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