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In subcellular fractionation, SLC25A40 was shown to co-localize with VDAC, a mitochondrial protein (Fig
Ingestion of 4 g synthetic carnosine alone by adult humans does not affect its concentrations in plasma due to high carnosinase-1 activity in plasma that rapidly hydrolyzes carnosine into -alanine and histidine, but does increase the urinary output of carnosine (Gardner et al
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