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Macrophage recruitment in obese adipose tissue
In the pivotal STEP 1 trial, patients receiving semaglutide 2.4mg weekly achieved average weight loss of 14.9% over 68 weeks
The side effects were similar to the injectable version of Wegovy and were generally mild to moderate in severity, the company said
Medication history: prior GLP-1, GIP, insulin, or sulfonylurea use
It found that patients with diabetes who were prescribed semaglutide, which is marketed as Wegovy and Ozempic, were about four times more likely to be diagnosed with non-arteritic anterior ischemic optic neuropathy (NAION), an eye condition that is painless but cannot be treated or cured
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