Failing to pinch the skin fold before injection in lean individuals can result in the needle reaching muscle tissue rather than subcutaneous fat
Acta Mater Med
It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation
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In a study on rats, DSIP demonstrated an analgesic effect, increasing the threshold for pain response (Gyermek et al., 1981)