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Targeting BCL-XL and BCL-2 by PROTAC 753b effectively eliminates AML cells and enhances efficacy of chemotherapy by targeting senescent cells
Alternative Protocol (3 mL = 16.67 mg/mL
Since most stability estimates cap out at 28 to 60 days, you would need to either: Reconstitute the full 60 mg and accept potential degradation in weeks 9-12 Consider reconstituting only a portion of the powder (not recommended as it is nearly impossible to accurately divide lyophilized powder) Accept that stability may extend beyond the conservative 28-day estimate, especially with proper BAC water use and refrigeration Many experienced researchers report viable solution quality at 8 to 10 weeks when using bacteriostatic water and maintaining strict refrigeration
These include neuroprotective benefits, mitigating drug toxicity, anti-aging benefits, analgesic effects, and treatment of metabolic disease [21, 22, 23, 24]
