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This may be the initial dose and dose escalation of TZP were different from the others (In this study, initial dose was 5 mg, instead of 2.5 mg, and at the rate of 2 weeks for dose escalation was faster compared to 4 weeks in other studies), which may lead to more injection-site reactions and GADE

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Studies show additive increases in circulating GH and IGF-1 levels while preserving natural feedback loops

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