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Furthermore, Al-Otaish et al

Figure 1 The first process consists in the de novo synthesis of GSH from its component amino acids, through two ATP-consuming enzymatic reactions

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205 Following carboplatin treatment, ACSL1/FSP1 activation inhibits ferroptosis and reduces the sensitivity of cancer cells to platinum chemotherapy, promoting cell survival and metastasis

demonstrated that topical GHK-Cu at concentrations as low as 0.01% stimulated collagen synthesis in human dermal fibroblast cultures, and clinical application of GHK-Cu-containing creams improved skin thickness and elasticity in photoaged skin over 12 weeks [1]