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In addition to the cardiovascular protection afforded by glucose metabolism regulation, a large body of evidence from animal and cellular studies has corroborated the beneficial effects of GLP-1 RAs on conditions such as heart failure (HF), hypertension, and ischemic cardiomyopathy
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Serious concerns like pancreatic or thyroid cancer remain unconfirmed due to their rarity.[6] While the risk of hypoglycemia is generally low, it increases when combined with insulin or sulfonylureas.[2] Upper respiratory infections were reported in several trials, particularly with oral semaglutide, though the mechanism remains unclear
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