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Through its ability to block NOTCH1 maturation, CHAC1/BOTCH was identified as Neuroprotective Gene 7 (NPG7) due to its protective effects in neuronal contexts

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Common side effects may include gastrointestinal discomfort, nausea, or diarrhea

Furthermore, neuroinflammation driven by systemic oxidative stress disrupts the delicate balance of autonomic signaling in the brain, leaving patients stuck in a perpetual, exhausting 'fight or flight' state

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