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The unique HC contains three extracellular domains (1, 2, and 3) followed by a transmembrane part and a cytoplasmic tail, where the extracellular domains are paired up with the soluble 2m [23, 24]

Cozza G, Rossetto M, Bosello-Travain V, Maiorino M, Roveri A, Toppo S et al (2017) Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: the polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center

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It achieves this by stimulating the formation of new blood vessels, a process known as angiogenesis, which is crucial for delivering nutrients and oxygen to healing tissues

Goar explains

Oxidative stress is one of the primary drivers of the visible and internal signs of aging