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Specific peptides derived from whey protein directly stimulate GLP-1 secretion (Watkins et al., 2021)
Oncotarget 6 , 4170641721 (2015)
How These Peptides Work in the Body CJC 1295 stimulates pituitary GH release via GHRH receptors, ipamorelin acts on ghrelin receptors to independently trigger GH secretion, and retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors to reduce appetite and increase energy expenditure
PMC 9200736
But you should be careful when using it long-term
This means ipamorelin produces clean GH pulses without the downstream hormonal disruption that limits other secretagogues
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