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Additional regional factors such as high baseline HBV endemicity (5-18%), dietary aflatoxin exposure, and lower NAFLD prevalence further limit direct extrapolation (105)
Other techniques including immunohistochemistry and immunogold can further evaluate the levels of the various antioxidant enzymes in tissues and cells
Limited randomized controlled trials suggest these therapies may be beneficial and have similar response rates
This ultimately led to a significant inhibition of tumor growth in CRC mouse models (29)
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