These statistical analyses were performed using GraphPad v8.0 (GraphPad Software, La Jolla, CA, USA) and XLSTAT v19.1 software (Addinsoft, Paris, France)
1 Participants taking semaglutide 2.4 mg had a 20% reduction in major adverse cardiovascular events (MACE), including cardiovascular death, non-fatal heart attack, and non-fatal stroke, compared to placebo
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Pooled results from seven non-pharmacological trials were associated with a statistically significant 48% relative reduction of TIN risk with low heterogeneity and the pooled results from six pharmacological trials were associated with a significant 20% relative reduction of TIN risk with moderate heterogeneity
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