By acting on the peripheral endings of sensory nerve fibers, Botox reduces the release of pain-transmitting neuropeptides, lowers nerve hypersensitivity, and decreases the frequency and intensity of pain attacks
doi:10.1038/s41392-024-01951-9 Uusitupa M, Khan TA, Viguiliouk E, et al
(PubMed) 1Pastori D, Carnevale R, Cangemi R, et al
Carnitine and acetylcarnitine can be taken up into ocular tissues from the circulation to support the function of ocular tissues such as the retina [313,314,315]
Hashimoto T, Hussien R, Brooks GA
There is no clinical trial data specifically studying this approach, but some prescribers report anecdotally that patients maintain better long-term responses with periodic dose reductions