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For other parenteral routes such as subcutaneous and intramuscular injections, the bioavailability may still be close to 100 % for most therapeutic drugs (F = 0.751), since little or no significant metabolism of the drug occurs in the skin or muscle and these small molecules (MW 0 min) compared to the intravenous route
Serdar Z, Gr E, Develiolu O
[19], Tietz et al
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The intimal layer is 20- 40mm thick in cross-section and the subintima can be up to 5mm in thickness (16, 17)
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