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Particularly useful for patients who started with borderline metabolic markers

Endpoints frequently measured include the activity of alkaline phosphatase (ALP), an early marker of osteoblast differentiation, the expression of the master osteogenic transcription factor Runx2, and the deposition of a mineralized matrix, which can be visualized with Alizarin Red staining

3-Methylglutaconic acid is tied to breaking down leucine and to cellular energy production, and is closely related to its companion marker 3-methylglutaric acid

BPC-157 is used in cell-based assay research examining its interactions with growth factor receptor signalling pathways, including FAK-paxillin pathway activation and downstream phosphorylation events

Intraperitoneal injection, used in mouse studies, is not appropriate for human use

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