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This results in effects secondary to both GLP-1 and GIP receptor activation, such as increased beta cell function and inhibition of glucagon secretion [35]
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Overall, this trial was designed to precisely determine the dose-response relationship, efficacy, and safety of Cagrilintide compared with placebo and liraglutide, while employing advanced statistical methods to ensure reliable interpretation of treatment effects under both ideal and real-world adherence conditions
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Trial results vary by drug, dose, baseline weight, adherence, side-effect tolerance, and whether patients can stay on treatment
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