GLP-1 medications start at low doses that are gradually increased, so full therapeutic effects develop over time as you reach the maintenance dose
Interested in this topic, you can read more in several articles: fat loss vs weight loss, the effects of medically induced weight loss on skeletal muscle, changes in fat-free mass during significant weight loss: a systematic review, and fat-free and skeletal muscle loss with GLP-1 treatments
Chu X, Tian W, Ning J, Xiao G, Zhou Y, Wang Z, et al
May slow cartilage degradation in osteoarthritis
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Its available on prescription through the NHS and, like tirzepatide , should only be taken under medical supervision if you meet the eligibility criteria