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Five GLP-1RAs are available in Australia (dulaglutide, exenatide BD, exenatide QW, liraglutide, and lixisenatide), one is undergoing regulatory approval (semaglutide), and three are currently available under the governments reimbursement scheme (dulaglutide, exenatide BD, and exenatide QW)

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Abbreviations and Acronyms 6MWD = 6-minute walk distance eGFR = estimated glomerular filtration rate GIP = glucose-dependent insulinotropic polypeptide GLP-1 = glucagon-like peptide 1 HFpEF = heart failure with preserved ejection fraction Funding Support and Author Disclosures The SUMMIT trial was funded by Eli Lilly and Company

Outcomes of trials so far have been largely negative