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This includes: Binders should be titrated slowly and paired with hydration and regular elimination to minimize Herxheimer reactions
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A 2022 double-blind, benchmark- and placebo-controlled RCT by Duperray, Sergheraert, and colleagues in the Journal of Cosmetic Dermatology (n=124 Asian women, 12 weeks) found that oral L-cystine plus reduced L-glutathione significantly lightened skin and reduced facial dark spot size at both 6 and 12 weeks versus placebo
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But over time, combined with exercise, it can support fat loss
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