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Some patients feel as though they want more frequent injections, and occasionally we test levels to see if they are receiving adequate replacement, but Im not sure how strong the evidence is to support this. GPs should consider periodic vitamin B12 testing of higher-risk patients who take metformin, even if they dont display symptoms of deficiency, the UK medicines regulator said earlier this year

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The buffered form of Vitamin C (sodium ascorbate) combined with a proprietary liposomal delivery system decreases issues of bowel intolerance,and is less likely to cause gastrointestinal side effects by bypassing absorption constraints posed by thegut

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Metal-based systems (MnO, Cu 2 , Fe 3 ) deplete GSH and generate ROS, with imaging potential, though metal toxicity and accumulation are concerns