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Lipotropic compounds play an important role in the bodys lipid metabolism process
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p53-pS15 is a major focal point in p53 activation to mediate p53-dependent transcription or growth arrest, Ser 15 phosphorylation triggers a sequence of additional sites phosphorylation in p53 (including Ser9, -20, -46 and Thr18) that contribute further to p53 activation 28
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The use of CDK-inhibiting drugs, especially CDK4 and CDK6, induces cellular senescence by inhibiting the transition of the cell from the G1 to the S phase, simultaneously inhibiting its proliferation [81]
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