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In contrast, Ex-4 is only found in the venom of the lizard Heloderma suspectum , with the endogenous GLP-1 being DDP-4 sensitive and 84% identical at the amino acids level to human GLP-1 14,15

It improves insulin sensitivity, reduces blood pressure, and lowers cholesterol levels

It goes away pretty quickly once your body gets adjusted to the peptide

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That distinction becomes even more important after 40, when muscle loss naturally accelerates with age

As Drucker pointed out to me: We know that GLP-1 is not getting directly to those neurons, but it's activating pathways that turn on those neurons