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In addition to this endocrine action, the local inhibitory effect of DPP-4 inhibitors on GLP-1 degradation in the intestinal mucosa may contribute to favorable metabolic regulation by stimulating the autonomic afferent nervous system (10, 19)

Lavar con 3 mL de solucin acuosa de cido clorhdrico 10 mmol/L, descartar el lavado, secar al vaco durante 1 min, eluir con 2 mL de solucin de metanol con amonaco al 4%, y recoger el eluato en un tubo de centrfuga de 15 mL

10.1111/cen.12641 33 KhalikovaM.JireJ.HorekO.DouaM.KueraR.NovkovL

Incretin-based therapy and pancreatitis: accumulating evidence and unresolved questions

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Is 5-amino-1MQ a peptide