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(Migraines are considered chronic when someone has a headache on 15 or more days a month for at least three months.) The researchers divided the participants into two groups: Those who started taking a GLP-1 medication for another condition (such as type 2 diabetes or obesity) within a year of being diagnosed with chronic migraines, and those who started taking topiramate (a prescription medication used to prevent migraine headaches) during the same period

Nystrom T, Gutniak MK, Zhang Q, Zhang F, Holst JJ, Ahren B, Sjoholm A: Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease

Key highlights: Demonstrated sustained improvements across symptomatic, clinical, endoscopic, histologic, and quality-of-life endpoints Benefits seen even in ~27% of patients who had failed prior biologics or advanced therapies Long-term safety profile consistent with prior findings no new safety signals Among patients continuing from blinded maintenance to the open-label extension, 12% reported serious adverse events, 7% discontinued due to adverse events Approved for UC and Crohns disease in 44 countries These results (from the LUCENT-3 extension) were shared at UEG Week 2025 in Berlin and mark a significant milestone in the pursuit of durable, steroid-free remission for IBD patients

In addition, L-carnitine benefits other aspects of health, particularly joint health and healthy brain function and cognition.* Supports Energy Production Without L-carnitine, cellular energy balance would be compromised because fatty acid oxidation would be limited

The FDA was reviewing nominations for the so-called 503B bulks list, which identifies drug ingredients that outsourcing facilities may use in compounding