If constipation becomes problematic, increasing dietary fibre gradually and considering a gentle laxative such as macrogol (typically first-line per NHS guidance) may help
After expanding the weight - loss indication, GLP - 1 drugs also have a strong consumer attribute
Any menstrual changes are likely secondary to the weight loss and metabolic effects of the medication rather than a direct action on reproductive hormones
Overall, we think this is an acceptable profile & orfo[rglipron] 36 mg generally looks in line vs Wegovy 2.4 mg/oral sema[glutide] 50 mg, Akash Tewari, global head of biopharmaceutical research with Jefferies, wrote in a research note
and feeling sick is the most common reason patients cited for stopping
This article originally appeared in our print magazine, First For Women .