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19,67,73,74 Newly proliferated reactive astrocytes form borders that separate damaged, inflamed, and fibrotic tissue from adjacent viable neural tissue, and during this border formation newly proliferated astrocytes become transcriptionally reprogrammed to adopt new cellular interactions with non-neural cells
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Hematoxylin (Solarbio, G1120) was used to stain the nuclei, while eosin (Solarbio, G1120) was used to stain the cytoplasm
b KruskalWallis rank sum test
Separate work demonstrated a two-fold increase in the production of metalloproteinase inhibitors (TIMPs), which regulate extracellular matrix remodeling [3]
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