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The research: SURPASS and SURMOUNT trials did not identify cortisol dysregulation as either an adverse effect or a benefit of tirzepatide
Despite this, the pharmacological toolbox remains thin
Wahab S et al
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The Nuclear receptor coactivator 4 (NCOA4) is an important molecule that mediates ferroptosis, and silencing NCOA4 decreases the level of liable iron pools and inhibits ferroptosis [14, 27]
Sulforaphane protects against rotenone-induced neurotoxicity in vivo : Involvement of the mTOR, Nrf2 and autophagy pathways
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