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The process is gradualusually taking several weeks to a few months

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During rapid correction of severe anemia, potassium may need monitoring in some higher-risk patients

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However, in the presence of oxidative or nitrosative stress, GST can form homodimers that alter the reduced states of cysteine residues in its structure, resulting in JNK dissociation from the GSTJNK heterocomplex and causing subsequent activation of the c-Jun protein