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The patient profile for non-GLP-1 peptides Metabolically healthy baseline: Fasting glucose, insulin, and lipids are within range, but stubborn fat remains

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While semaglutide itself is not majorly metabolized by CYP3A4, the risk comes from compounding effects when grapefruit is combined with other medications you may take simultaneously, such as blood pressure drugs, cholesterol medications, or antihistamines