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Keep fluids separate from meal volume, sipping through the day rather than drinking a large glass with food
Key interactions (including with anticoagulants and antiepileptics) and contraindications are detailed in the relevant SmPCs (emc)
Dihexa is dosed for steady-state accumulation because of its multi-day half-life
Additionally, the body naturally responds to sustained calorie restriction by lowering metabolic ratea protective mechanism that conserves energy when intake decreases
