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Back to Journals Clinical, Cosmetic and Investigational Dermatology Volume 10 Glutathione and its antiaging and antimelanogenic effects Authors Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P Received 21 November 2016 Accepted for publication 10 February 2017 Published 27 April 2017 Volume 2017:10 Pages 147153 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Jeffrey Weinberg Sinee Weschawalit, 1 Siriwan Thongthip, 2 Phanupong Phutrakool, 3 Pravit Asawanonda 1 1 Department of Medicine, Division of Dermatology, 2 Chula Clinical Research Center, 3 Chula Data Management Center, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Background: Previous studies showed that supplementation of reduced form of glutathione (GSH, 500 mg/d) has a skin-lightening efficacy in humans
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Because cysteine availability is the principal bottleneck in glutathione synthesis, increasing intracellular cysteine supply drives higher GSH production
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