Interestingly, while the exposure of brain microvascular endothelial cells to the HIV-1 Tat protein leads to decreased expression of claudin-1, claudin-5, and ZO-2, the expression of ZO-1 and occludin remains unchanged [186]
Satellite cell activation: Skeletal muscle has a population of stem-like satellite cells that, when activated, differentiate into myoblasts and fuse with existing muscle fibers literally adding new nuclei and increasing muscle fiber density
PloS Comput
Moreover, evidence supporting EGCGs neuroprotective effects via BBB-mediated anti-neuroinflammation and reduction of oxidative stress includes: (i) EGCG enhances dopamine neuron activity in the gut, decreases serotonin levels in the colon, and increases hippocampal 5-hydroxytryptamine levels by enhancing intestinal permeability (215217)
Metabolic Efficiency: Researching the blends impact on basal metabolic rate, adipose tissue oxidation, and nitrogen retention