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After 24 h of co-culture with G/D-CuP, NIH/3T3 cells displayed well-spread morphology and high viability, as demonstrated by both 3D and 2D Calcein-AM fluorescence imaging via CLSM (Supplementary Fig

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Semaglutide has an isoelectric point of 5.4, shows maximal degradation between pH 4.5 and 5.5, and is formulated in Ozempic at pH 7.4 with a phosphate buffer deliberately away from that window

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Titration is typically every 4 weeks if tolerated, mirroring the manufacturer-recommended Wegovy schedule