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This interdependence is yet to be systematically investigated
Neither peptide is FDA-approved for human use, but both are available as compounded prescriptions through licensed U.S
Some patients have a threshold effect: tolerable constipation at 1.0 mg, sudden severe constipation at 1.7 mg, no further worsening at 2.4 mg
Because of this, it has gained attention in inflammation research
2011 Mar;110(3):774-80
The fuller tolerability picture is covered in the AHK-Cu side effects article
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