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When the NNMT enzyme is overactive, its often associated with insulin resistance, a condition where your cells dont respond well to insulin and cant easily take up glucose from your blood

However, the progress is slow

Keeping regular follow-up appointments with their healthcare provider to assess treatment efficacy and adjust the regimen as needed

Long-term use of cortisone injections can cause various side effects, including tissue atrophy, weakened tendons, and blood sugar elevation

Oral Supplementation Oral B12 supplements are widely available, but their effectiveness varies

AOD-9604 Regulatory Status As of June 2026, AOD-9604 is not FDA-approved for any therapeutic use