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Kankofer M, Wawrzykowski J, Giergiel M
Superoxide dismutase (SOD) catalyzes the dismutation reaction of superoxide anion radicals: 2- + 2- = 2 + 22 During the reaction, hydrogen peroxide is formed, which is able to inactivate SOD, so SOD always works in tandem with catalase, which quickly and efficiently breaks down hydrogen peroxide into neutral compounds: 2H2O2 = 2H2O + O2 The property of SOD to reduce the formation of peroxynitrite is due to its ability to reduce the concentration of the superoxide radical in the cell, which also limits its availability for the Fenton reaction
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