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J Interferon Cytokine Res 31:653659 Malaguarnera M, Vacante M, Giordano M, Pennisi G, Bella R, Rampello L, Malaguarnera M, Li Volti G, Galvano F (2011) Oral acetyl-l-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study
Distribution of weight loss according to the percentage of initial body weight lost following treatment
The study successfully met its primary endpoint with the highest dose achieving 63.5% clinical response versus 27% placebo at Week 12 and 30.2% clinical remission versus 11.1% placebo, with favorable tolerability and continued improvement through Week 28, though the study completion date and final comprehensive results are pending presentation at upcoming medical congresses
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