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Concurrent iron-deficiency anemia and folic acid deficiency may result in a blunted or impeded response to methylcobalamin therapy
Cleveland Clinic
Different Forms of Vitamin B12 It might surprise you to learn that not all vitamin B12 is created equal
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As we age, our bodies produce less of the stomach acid that is needed to separate the B12 so it can be attached to the intrinsic factor so the body has a more difficult time getting an adequate amount of vitamin B12
Each works through a different mechanism, and the evidence levels are very different
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