In particular, pain management, like all other medical interventions, is not guaranteed to have the same outcome for every clients health
Subgroup analyses revealed that weight loss was greater in overweight versus obese participants, in unhealthy versus healthy participants, with daily doses 600 mg, and for intervention period shorter than 10 weeks
Lauro C, Chece G, Monaco L, Antonangeli F, Peruzzi G, Rinaldo S, et al
There is also an increased risk of side effects when combining medications that affect similar systems in the brain
This temporary discomfort is generally outweighed by the long-term benefits of reaching the optimal therapeutic dose
The 0.25mg starting dose rarely produces significant weight loss