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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies
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Weve already encountered superoxide dismutase 2 (SOD2), which converts the superoxide anion into hydrogen peroxide
Glutathione also plays a fundamental role as a direct support to the immune defense against inflammation, infections, viruses, bacteria, etc
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