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Previous studies have shown that integrins and related pathways are crucial for the dynamic regulation of cell differentiation and the phosphorylation/dephosphorylation status of a protein phosphatase in the signaling pathway, which are related to the oxidation/reduction status of cysteine residues on the protein phosphatase [40, 41]
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Histone deacetylases (HDACs), in particular, have emerged as key regulators of astrocyte-mediated neuroinflammation and neurodegeneration
We do not know the optimal human dosing, long-term safety profile in humans, or whether animal results translate directly to human outcomes
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