Although semaglutide (Ozempic/Wegovy) has largely overtaken liraglutide in clinical preference due to its weekly dosing and greater weight loss efficacy, liraglutide retains several advantages: it has over 15 years of post-marketing safety data, cardiovascular outcome data from the landmark LEADER trial, and pediatric approvals for both diabetes and obesity
Most evidence for MIC B12 is anecdotal or from small uncontrolled studies
Early animal and small human studies suggest it is generally well tolerated in the short term, but we do not yet have large, longterm trials
Vitamin B12 plays a vital role in supporting energy production, maintaining healthy nerve function, and forming red blood cells
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Antioxidant mechanisms: Fenton reaction prevention through copper chelation, SOD upregulation, Nrf2 pathway activation, and lipid peroxidation quenching