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These metabolites, along with others like prostaglandin E2 (PGE2) and eicosanoids, play a pivotal role in the immunosuppressive functions of MDSCs within the tumor microenvironment [39]
Separate direct evidence from theory
2025 Apr;242(4):71724
These initial changes reflect anti-inflammatory effects and early tissue repair processes
Transports fatty acids into mitochondria for energy production, supporting muscle recovery and reducing fat storage
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
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