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Patients should be referred urgently if they have neurological symptoms, if the diagnosis is unclear, or if there is inadequate clinical response to treatment

A trained clinician should demonstrate proper injection technique to minimize local irritation

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Kidney Impairment Semaglutide base is generally regarded as safe in patients with mild to moderate kidney disease

Other dermatologic photoprotection contexts and early studies Early EPP photoprovocation pilot (two 20 mg implants, 60 days apart) reported ~11fold increases in time to intolerable pain under artificial white light