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While glutathione benefits far outweigh any potential risk factors, certain risk factors may exist

Arch Neurol 69:836841 Hardan AY, Fung LK, Libove RA, Obukhanych TV, Nair S, Herzenberg LA, Frazier TW, Tirouvanziam R (2012) A randomized controlled pilot trial of oral N-acetylcysteine in children with autism

Self-administration can carry risks such as infection, allergic reactions, improper dosing, pain, bruising, and unexpected side effects

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Seasonal considerations matter too