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The American Academy of Pediatrics updated its guidelines in 2023 on childhood obesity to say that medication, as well as bariatric surgery, should be offered earlier as treatment options alongside lifestyle changes

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In research it is studied for melanocortin pathway pharmacology, central appetite regulation, and pigmentation signaling

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This was the first study to systematically demonstrate that tirzepatide not only induces substantial weight loss but also shows improvements in sleep-disordered breathing among obese individuals