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Understanding the broad mechanism of action is essential when considering whether GLP-1 medications might influence hormonal balance more generally, particularly given their increasing use in diverse patient populations including those with metabolic syndrome, polycystic ovary syndrome (PCOS), and obesity-related endocrine dysfunction
Support was also received via Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) Grant Number JP18dm0207001 (TCS) and a research grant from the RIKEN Center for Brain Science
Additionally, the gut microbiome affects the production of these SelPs by influencing the bioavailability of Se and its incorporation into metabolic pathways
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