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Die duale Rezeptor-Aktivitt macht es zu einem einzigartigen Werkzeug gegenber reinen GLP-1-Agonisten

Sakamoto N et al

Dual incretin agonists are known to subtly modulate the mesolimbic reward pathways, affecting dopamine and serotonin signaling

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mean increases in resting heart rate of 1 to 4 beats per minute (bpm) were seen with routine clinical monitoring in semaglutide-treated patients vs

While in vivo data to address this question are limited, results from drug interaction studies suggest that escitalopram, at a dose of 20 mg, has no 3A4 inhibitory effect and a modest 2D6 inhibitory effect [see Drug Interactions (7)]