There is an increase due to melanin deposits in the basal cell layer, lamina propria, or both in the microscopic characteristics of the macule
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A recent study further revealed that TIMM17B may impact ferroptosis and chemotherapy resistance in breast cancer through its effect on GPX4 ( Studies have demonstrated that erastin significantly enhances the chemotherapeutic efficacy of temozolomide, cisplatin, cytarabine, and doxorubicin by inducing ferroptosis ( 3 Ferroptosis-related drug resistance in different subtypes of breast cancer Chemotherapy is a critical therapeutic strategy for breast cancer, which remains a complex process involving multiple genes and signaling pathways
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integrated bioinformatic analysis with in vivo experiments for validation utilizing OVA-induced guinea pigs
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